3Decision®️
Bringing Structural Data Analytics to The Masses
3decision® is a collaborative platform for storing, analyzing and sharing protein-ligand 3D structures, sequences, and associated data
Explore pocket on structures | Visually explore druggable pockets on your structure
Consensus pocket exploration on homologous proteins | Rapidly gather all pockets/ligands of all structures of your proteins and assess druggability and specificity
Design and dock a new ligand | Quickly dock the compound into the binding site. Validate the docking poses based on protein-ligand interaction statistics.
Visualize public and proprietary electron density maps | Get easy access to public and private electron density maps
Sketch, modify or import compounds | Use the sketcher to modify the co-crystallized ligand or create a new one. You can also import compounds directly from ChEMBL or an internal ligand library.
Detailed information about your structure | Get info on biomolecules and ligands, and associate documents to structures
Browse & add structure and sequence annotations | Configure your own structure and sequence annotations and show them in 3D
Structure- and ligand-based off-target screening | Use structure-based technologies, ChEMBL and ligand fingerprints to search for putative off-targets or novel opportunities
Browse all ligands of your proteins | 2 clicks away to visualize and locally superimpose all structures with ligands of your protein of interest
Keep your R&D agile and sustainable
Get ready for future massive intake of structural information (X-ray, NMR, Cryo-EM, etc.). Organize and store your PDB structures, in house structures, and in silico models in a centralized database. Give all researchers easy access to the same knowledge via a web browser.
Increase your productivity
Save time comparing similar pockets and ligands. Create and test hypotheses on the fly. Visualize hot spots or mutations in 3D with one click. Share ideas with colleagues quickly and easily.
Integrate with other applications
Access 3decision programmatically through a flexible REST API. Export analyses and data to common data formats.
Benefit from collective intelligence
Extract and apply knowledge that has been generated over time by different project teams and research programs. Maximize the value of public and proprietary data by keeping it alive and searchable.
Facilitate Collaboration
Share 3D views and highlighted results the way you see them. Share your models and hypotheses with the project team. Allow colleagues to dock their new compound ideas in a structure.
Secure your data
Keep your structural data safe and whole. Guarantee access to your data in the long run. Make complex analyses reproducible.