How accurate are antibody-antigen AF3-predicted complexes? - A PD-1 case study

Starting from AF3 PD-1/antibody complexes not included in the training dataset, we assessed the ability of AF3 to agnostically predict protein-protein interfaces and epitopes.

Download our case study to discover:

• Where AF3 models showed the biggest accuracy

• Importance of post-translational modifications when generating models

• Limitations of the AI-predictions