Discngine Labs: Harnessing the Potential of Structural Data for Ideation in Drug Discovery

As advancements in experimental (e.g. Cryo-EM) and computational (e.g., AlphaFold) methods continue to surge, the demand for tools to efficiently handle protein structure data and extract insights for new compound ideation has become paramount.

Our sixth Discngine Labs will showcase a live demo on how to navigate through the vast landscape of protein structures to generate new design ideas on the fly with 3decision – Discngine’s structural repository and analytics software. Additionally, the event will feature a stimulating panel discussion with pharma experts in the field, discussing the critical aspects of efficient structural data management for new compound designs.

By attending this event, you will discover:

  • The transformative impact of structural data to inspire your next compound design

  • How to gather design ideas using cross-target interaction and pocket similarity searches with 3decision

  • Current pitfalls and best practices for harnessing structural data in compound design

Speakers

Roundtable chair

 

Simone Fulle

Head of Protein Engineering in Computational Drug Design area

Novo Nordisk

Panelists

Daria Goldmann

Artificial Intelligence Expert, Integrated Drug Discovery unit

Sanofi 

David Thompson

Senior application scientist

CCG - Chemical Computing Group

 

Simone Culurgioni

Head of Crystallography

Exscientia

 
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How to best exploit 3D protein structures for ideation in SBDD

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Understanding selectivity of CLK kinase inhibitors: structural insights with 3decision®